Fig. 2. The tumor microbiome shows significant differences among PDAC subtypes.

a–b Barplots denote the relative abundance of predominant microbiota constituents at the genus level for each sample (a) and for each subtype (b). c Boxplots of microbial diversity measures at the genus level, including richness (observed genera), Shannon index and Bray-Curtis metric distance. P values were determined by ANOVA with post-hoc test. d PCoA plot of the tumor microbiome at the genus level based on Bray–Curtis dissimilarity. The ellipses indicate the 90% confidence interval.