Skip to main content
. 2021 Aug 31;11:17404. doi: 10.1038/s41598-021-97081-1

Table 2.

Values of the correlation coefficient and release exponent obtained for mathematical models applied to DOX release from chitosan nanoparticles.

Zero-order First-order Higuchi Korsmeyer-Peppas
R2 R2 R2 R2 n
pH: 4.5 0.7570 0.8469 0.9243 0.9878 0.2472
pH: 5.5 0.7788 0.8152 0.9378 0.9862 0.3267
pH: 6.5 0.7847 0.7996 0.9367 0.9787 0.3773
pH: 7.4 0.7689 0.7790 0.9306 0.9814 0.3267