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. 2021 Aug 31;12:5189. doi: 10.1038/s41467-021-25402-z

Table 1.

Demographic characteristics of the study participants in the training and validation datasets.

Variable Training dataset Validation dataset
Cases (%) Controls (%) P valuea Cases (%) Controls (%) P valuea
Age
  Mean (SD) 48.38 (11.07) 49.22 (10.64) 2.15E−01 49.30 (10.83) 50.98 (10.91) 1.07E−02
  < 28 16 (3.44) 13 (2.21) 4.23E−01 7 (1.64) 10 (1.33) 1.06E−02
  28–59 377 (81.08) 477 (80.98) 347 (81.26) 556 (74.03)
  > 59 72 (15.48) 99 (16.81) 73 (17.10) 185 (24.63)
Sex
  Men 349 (75.05) 453 (76.91) 5.29E−01 330 (77.28) 581 (77.36) 1.00E+00
  Women 116 (24.95) 136 (23.09) 97 (22.72) 170 (22.64)
Smoking
  Never 174 (37.42) 217 (36.84) 7.59E−01 182 (42.62) 335 (44.61) 3.79E−01
  Formerb 34 (7.31) 37 (6.28) 27 (6.32) 34 (4.53)
  Current 257 (55.27) 335 (56.88) 218 (51.05) 382 (50.87)
Salted fish
  Yearly or less 314 (67.53) 381 (64.69) 5.84E−02 373 (87.35) 612 (81.49) 1.62E−02
  Monthly 102 (21.94) 162 (27.50) 48 (11.24) 113 (15.05)
  weekly or more 49 (10.54) 46 (7.81) 6 (1.41) 26 (3.46)
Education
  Illiterate or primary school 183 (39.35) 205 (34.80) 2.55E−01 183 (42.86) 284 (37.82) 2.22E−01
  Middle school 192 (41.29) 244 (41.43) 156 (36.53) 292 (38.88)
  High school 70 (15.05) 113 (19.19) 73 (17.10) 134 (17.84)
  College or higher 20 (4.30) 27 (4.58) 15 (3.51) 41 (5.46)
Family history
  No 406 (87.31) 568 (96.43) 5.46E−08 389 (91.10) 732 (97.47) 1.97E−06
  Yes 59 (12.69) 21 (3.57) 38 (8.90) 19 (2.53)

a The P value was calculated using a two-sided t-test. Other P values for categorical variables were calculated using χ2 tests.

b Individuals who had quit smoking more than 1 year before the interview were defined as former smokers.