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. 2021 Aug 31;11:17444. doi: 10.1038/s41598-021-96935-y

Table 2.

Basic characteristics of the studied genetic variants.

SNP Variant type Gene Base change NCBI assembly location (Build GRCh38)a TaqMan SNP assay ID MAFb
GBM patients Control group ALL EUR CEU
rs1047972 Missense AURKA C/T Chr.20:56386407 AHX1IRW 0.162 0.146 0.150 0.182 0.157
rs2273535 Missense AURKA A/T Chr.20:56386485 C_25623289_10 0.299 0.238 0.310 0.216 0.177
rs8173 3′ UTR AURKA G/C Chr.20:56369735 C_8947675_10 0.354 0.305 0.486 0.282 0.232
rs911160 Intron AURKA G/C Chr.20:56382507 C_8947670_10 0.300 0.276 0.447 0.246 0.202
rs2289590 Intron AURKB C/A Chr.17:8207446 C_15770418_10 0.375 0.415 0.453 0.415 0.389
rs2241909 Synonymous AURKB A/G Chr.17:8205021 C_22272900_10 0.332 0.332 0.379 0.340 0.303
rs11084490 5′ UTR AURKC C/G Chr.19:57231104 C_27847620_10 0.152 0.223 0.132 0.165 0.177
rs758099 Intron AURKC C/T Chr.19:57231966 C_2581008_1_ 0.162 0.302 0.375 0.255 0.253
rs42873 Intron PLK1 G/C Chr.16:23683411 C_2392140_10 0.354 0.208 0.234 0.215 0.192

ALL all phase 3 individuals, CEU Utah residents with Northern and Western European ancestry, EUR European population, GBM glioblastoma multiforme, MAF minor allele frequency, SNP single nucleotide polymorphism, UTR untranslated region. ahttps://www.lifetechnologies.com. bMAFs extracted from 1000 Genomes Project Phase 3.