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. 2021 Apr 19;2021(4):CD011535. doi: 10.1002/14651858.CD011535.pub4

Goldust 2019.

Methods Randomised controlled clinical trial study, 4 were randomly assigned to receive combination therapy (efficacy assessments were performed)
Participants 48 patients with moderate‐to‐severe plaque psoriasis
Interventions In this 24‐week study,
intervention 1: adalimumab sc 80 mg at weeks 1 and 2 then 40 mg every 2 weeks
intervention 2: no intervention or placebo ??
Co‐intervention: methotrexate 15 – 20 mg a week or methotrexate monotherapy
Outcomes PASI
Hospital Anxiety and Depression scale
Notes ABSTRACT