Table 1.
Baseline Characteristics of Studied MDS Cases
| Total = 100 cases | No | % | |
|---|---|---|---|
| Sex | Male | 54 | 54% |
| Female | 46 | 46% | |
| Diabetes | 24 | 24.00% | |
| Hypertension | 31 | 31.00% | |
| Smoking | 20 | 20% | |
| Cytopenia | Monocytopenia | 31 | 31% |
| Bicytopenia | 25 | 25% | |
| Pancytopenia | 44 | 44% | |
| WHO classification | MDS-SLD | 15 | 15% |
| MDS-RS | 7 | 7% | |
| MDS-MLD | 22 | 22% | |
| MDS-EB-1 | 13 | 13% | |
| MDS-EB-2 | 37 | 37% | |
| MDS del(5q) | 6 | 6% | |
| Cytogenetics | Favorable | 36 | 36% |
| Intermediate | 15 | 15% | |
| Poor | 49 | 49% | |
| IPSS-R | Very Low/Low | 33 | 33% |
| Intermediate | 37 | 37% | |
| High/Very High | 30 | 30% | |
| Transformation to Secondary AML |
No Transformation | 86 | 86% |
| Secondary AML | 14 | 14% | |
| Mortality | Died | 40 | 40% |
| Genotyping | GG Homozygotic type | 37 | 37% |
| GA Heterozygotic type | 38 | 38% | |
| AA Homozygous mutant | 25 | 25% |
MDS-SLD, myelodysplastic syndrome-single lineage dysplasia; RS, ringed sideroblastic; MLD, multilineage dysplasia; MDS-EB, myelodysplastic syndrome Excess blast