Table 3.

Univariate and Multivariate Analysis of Prognostic Factors of Overall Survival

	Univariate			Multivariate
	HR	95.0% CI	P	HR	95.0% CI	P
Age group (≥ 65 years)	5.2	2.7-10.2	< 0.001
Cytopenia			0.01
Bicytopenia	1.6	1.2-8.9	0.03
Pancytopenia	1.9	1.2-11.1	0.02
BM blast percentage >5%	8	2.2-19.3	0.1
Cytogenetics			< 0.001
Intermediate	3.01	0.51-17.7	0.16
Poor	31.5	1.9-22.9	0.001
IPSS-R			< 0.001			<0.001
IPSS-R (intermediate)	10.1	2.1-48.2	0.003	10.1	2.1-48.2	0.003
IPSS-R (high/very high)	49.1	24.6-64.2	< 0.001	49.1	24.6-64.2	<0.001
Genotyping			< 0.001
Heterozygous (GA)	9	2.4-26.5	< 0.001
Homozygotic mutant (AA)	28	11.7-36.4	< 0.001