Table 5.
Summary of cellular effects of tested articles in BioMAP systems.
| Test Article | Cytotoxicity: System (Concentration) | Antiproliferative effects: Cell type | Annotated biomarkers (at non-cytotoxic concentrations) | Physio- and pathological relevance |
|---|---|---|---|---|
| 3R4F | None | B cells Coronary artery smooth muscle cells Endothelial cells Fibroblasts |
10 | Inflammation-related activities Immunomodulatory activities |
| HTP | None | None | 3 | Immunomodulatory activities Tissue remodeling activities |
| HYB | None | None | 1 | Tissue remodeling activities |
| EVP | None | None | 3 | Immunomodulatory activities Tissue remodeling activities |