. 2021 Aug 28;29:100798. doi: 10.1016/j.ymgmr.2021.100798

Table 1.

Baseline characteristics of patient cohort.

Demographic characteristics
Parameter	Before Switch/ERT	After Switch/SRT
No. of patients	38	38
Sex, n (%)
Male	23 (61)
Female	15 (39)
Age at time of visit in years, mean (min-max)	47 (15-80)	51 (16-84)
Age at time of visit in years, mean (min-max)	N = 38	N = 38
Weight at time of visit in kilograms, mean (min-max)	78.7 (48.2-131.8)	80.0 (49.9-120.0)
Weight at time of visit in kilograms, mean (min-max)	N = 36	N = 36
No. of splenectomized patients, n (%)	4 (11)	4 (11)
Length of treatment in months, mean (min-max)	171.5 (24-312)	36.7 (5-85)
Length of treatment in months, mean (min-max)	N = 38	N = 38
Length of treatment in years, mean (min-max)	14.3 (2-26)	3.1 (0.4-7)
Length of treatment in years, mean (min-max)	N = 38	N = 38
Patient years of treatment	543	116
Patient years of treatment	N = 38	N = 38
CYP2D6-metabolizer phenotype, n (%)
Ultra-rapid	1 (3)
Extensive	26 (68)
Intermediate	9 (23)
Poor	2 (6)
Genotype, n (%)
N370S/N370S	19 (50)
N370S/Other	17 (45)
Other/Other	2 (5)