Table 5.
Clinical characteristics | All | Men | Women | Pinteraction with sex |
HR (95% CI) | HR (95% CI) | HR (95% CI) | ||
Sex (men, ref cat) | 0.83 (0.76 to 0.92)* | – | – | – |
Age (per 10 years) | 1.82 (1.71 to 1.92)* | 1.79 (1.65 to 1.94) | 1.87 (1.72 to 2.04) | 0.615 |
Current smoking | 1.38 (1.20 to 1.59)* | 1.32 (1.09 to 1.60) | 1.48 (1.20 to 1.82) | 0.359 |
Hypertension | 0.85 (0.77 to 0.93)* | 0.87 (0.76 to 0.99) | 0.80 (0.69 to 0.93) | 0.513 |
Diabetes | 1.28 (1.15 to 1.42)* | 1.33 (1.15 to 1.53) | 1.26 (1.08 to 1.47) | 0.853 |
Hyperlipidaemia | 0.87 (0.78 to 0.96)* | 0.84 (0.72 to 0.97) | 0.94 (0.81 to 1.10) | 0.055† |
Coronary artery disease | 1.10 (0.99 to 1.22) | 0.96 (0.83 to 1.12) | 1.26 (1.08 to 1.47) | 0.002† |
Congestive heart failure | 1.60 (1.42 to 1.80)* | 1.68 (1.43 to 1.96) | 1.51 (1.26 to 1.82) | 0.571 |
Ischaemic stroke | 1.44 (1.27 to 1.63)* | 1.31 (1.11 to 1.55) | 1.58 (1.32 to 1.90) | 0.067† |
ST-segment depression | 1.30 (1.15 to 1.48)* | 1.21 (1.02 to 1.44) | 1.39 (1.16 to 1.66) | 0.677 |
ln eGFR | 0.62 (0.57 to 0.68)* | 0.64 (0.57 to 0.72) | 0.60 (0.52 to 0.69) | 0.250 |
COPD | 1.71 (1.54 to 1.92)* | 1.58 (1.35 to 1.85) | 1.87 (1.59 to 2.21) | 0.143 |
Dementia | 1.53 (1.01 to 2.34)* | 1.33 (0.71 to 2.49) | 1.61 (0.91 to 2.91) | 0.749 |
Previous cancer | 1.45 (1.24 to 1.70)* | 1.40 (1.16 to 1.71) | 1.61 (1.21 to 2.14) | 0.283 |
ln hs-cTnT | 1.14 (1.09 to 1.18)* | 1.11 (1.06 to 1.17) | 1.18 (1.11 to 1.24) | 0.077† |
Analyses are adjusted for all assessed variables including hospital and admission year. Pinteraction refers to the interaction of sex with the multivariable-adjusted association of each respective covariate with clinical outcome.
*P<0.05.
†P<0.1.
COPD, chronic obstructive pulmonary disease; ln eGFR, log transformed estimated glomerular filtration rate; ln hs-cTnT, log transformed high-sensitivity cardiac troponin T; ref cat, reference category.