Fig. 2.

Electron microscopy of the Cp^KOcorpus callosum. (A) Electron micrographs of axons in the corpus callosum of control and Sox10-Cp^KO mice at P15 and P30. Scale bar = 8 μm upper panel; 2 μm lower panel. (B) Mean g-ratio values and percentage of myelinated axons. (C) Scatter plot of g-ratio values of myelinated axons at P15 and P30. Values are expressed as mean ± SEM. *p < 0.05, ***p < 0.001 versus control. (D) Representative western blots for MBP and CNP are shown. P84 was used as the internal standard and box-and-whisker plots are showing means ± SD. *p < 0.05, **p < 0.01, ***p < 0.001 vs. respective controls.