TABLE 4.
Baseline | 28 gestational wk | 36 gestational wk | Umbilical cord | |||||
---|---|---|---|---|---|---|---|---|
10 µg/d | 20 µg/d | 10 µg/d | 20 µg/d | 10 µg/d | 20 µg/d | 10 µg/d | 20 µg/d | |
All | n 118 | n 121 | n 118 | n 121 | n 118 | n 121 | n 31 | n 31 |
<50 nmol/L | 41.5 | 48.8 | 21.2 | 14.8 | 12.7 | 9.9 | 77.4 | 54.8 |
≥50 nmol/L | 58.5 | 51.2 | 78.8 | 85.2 | 87.3 | 90.1 | 22.6 | 45.2 |
Normal weight | ||||||||
<50 nmol/L | 35.9 | 34.1 | 20.5 | 9.8 | 10.3 | 4.9 | 81.8 | 38.52 |
≥50 nmol/L | 64.1 | 65.9 | 79.5 | 90.2 | 89.7 | 95.1 | 18.2 | 62.5 |
Overweight | ||||||||
<50 nmol/L | 43.6 | 55.0 | 15.4 | 12.5 | 7.7 | 7.5 | 88.9 | 60.0 |
≥50 nmol/L | 56.4 | 45.0 | 84.6 | 87.5 | 92.3 | 92.5 | 11.1 | 40.0 |
Obese | ||||||||
<50 nmol/L | 45.0 | 57.5 | 27.5 | 22.5 | 20.0 | 17.5 | 63.6 | 75.0 |
≥50 nmol/L | 55.0 | 42.5 | 81.5 | 77.5 | 80.0 | 82.5 | 36.4 | 25.0 |
Data are percentages, with differences in maternal and infant classifications of insufficiency (<50 nmol/L) and sufficiency (≥50 nmol/L) between treatment groups assessed using a chi-square test. Data at 28 and 36 gestational wk include imputed data; blood samples available for analysis at 28 gestational wk were n = 78 and n = 80, and at 36 gestational wk were n = 73 and n = 80, in the 10-µg/d and 20-µg/d treatment groups, respectively.
Significant difference in percentage prevalence of insufficiency and sufficiency in umbilical cord blood of normal weight women, P = 0.028. P < 0.05 considered significant.