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. 2021 May 8;114(3):1208–1218. doi: 10.1093/ajcn/nqab112

TABLE 4.

Prevalence of maternal 25(OH)D insufficiency and sufficiency throughout pregnancy and in umbilical cord at birth, in each treatment group1

Baseline 28 gestational wk 36 gestational wk Umbilical cord
10 µg/d 20 µg/d 10 µg/d 20 µg/d 10 µg/d 20 µg/d 10 µg/d 20 µg/d
All n 118 n 121 n 118 n 121 n 118 n 121 n 31 n 31
 <50 nmol/L 41.5 48.8 21.2 14.8 12.7 9.9 77.4 54.8
 ≥50 nmol/L 58.5 51.2 78.8 85.2 87.3 90.1 22.6 45.2
Normal weight
 <50 nmol/L 35.9 34.1 20.5 9.8 10.3 4.9 81.8 38.52
 ≥50 nmol/L 64.1 65.9 79.5 90.2 89.7 95.1 18.2 62.5
Overweight
 <50 nmol/L 43.6 55.0 15.4 12.5 7.7 7.5 88.9 60.0
 ≥50 nmol/L 56.4 45.0 84.6 87.5 92.3 92.5 11.1 40.0
Obese
 <50 nmol/L 45.0 57.5 27.5 22.5 20.0 17.5 63.6 75.0
 ≥50 nmol/L 55.0 42.5 81.5 77.5 80.0 82.5 36.4 25.0
1

Data are percentages, with differences in maternal and infant classifications of insufficiency (<50 nmol/L) and sufficiency (≥50 nmol/L) between treatment groups assessed using a chi-square test. Data at 28 and 36 gestational wk include imputed data; blood samples available for analysis at 28 gestational wk were n = 78 and n = 80, and at 36 gestational wk were n = 73 and n = 80, in the 10-µg/d and 20-µg/d treatment groups, respectively.

2

Significant difference in percentage prevalence of insufficiency and sufficiency in umbilical cord blood of normal weight women, P = 0.028. P < 0.05 considered significant.