TABLE 3.
Effects intervention on changes in α and β diversity metrics1
| Diversity measures (n = 343) | Treatment * Time (P value) |
|---|---|
| Chao12 | 0.16 |
| Shannon diversity2 | 0.15 |
| Phylogenetic distance2 | 0.21 |
| Weighted UniFrac3 | 0.72 |
| Unweighted UniFrac3 | 0.23 |
| Bray Curtis dissimilarity3 | 0.33 |
1
Effect of intervention (Treatment * Time) evaluated by linear mixed model adjusted for sex, study center, and baseline weight for chao1, Shannon diversity, and phylogenetic distance. Weighted UniFrac, unweighted UniFrac, and Bray–Curtis dissimilarity were evaluated by PERMANOVA (permutational multivariate analysis of variance) adjusted for sex, study center and baseline weight, and participants as strata.
2
α diversity indexes.
3
β diversity indexes.