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. 2021 Sep 1;21:979. doi: 10.1186/s12885-021-08726-3

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 5 — Western blot analysis of UTX expression and the downstream signaling pathway in the SAS and Cal 27 cell lines. The protein expression profiles of UTX, H3K27me3 status, EMT markers, cyclin D1 and CDK4 were examined in the presence or absence of GSK-J4 treatment in the OTSCC cells by Western blotting