Table 2.
Associations between UTX expression and clinicopathological parameters in 148 patients with oral tongue squamous cell carcinoma receiving surgical resection
| Parameters | UTX expression | |||
|---|---|---|---|---|
| Overexpression (N = 64) | Low expression (N = 84) | P value | ||
| Age | ||||
| <53y/o | 31 (48%) | 39 (46%) | 0.81 | |
| ≧53y/o | 33 (52%) | 45 (54%) | ||
| Sex | ||||
| male | 58 (91%) | 77 (92%) | 0.82 | |
| female | 6 (9%) | 7 (8%) | ||
| Pathological T status | ||||
| T1 + T2 | 34 (53%) | 56 (67%) | 0.10 | |
| T3 + T4 | 30 (47%) | 28 (33%) | ||
| Pathological N status | ||||
| N0 | 27 (42%) | 52 (62%) | 0.017* | |
| N1 + 2 + 3 | 37 (58%) | 32 (38%) | ||
| Pathological 8th AJCC Stage | ||||
| I + II | 19 (30%) | 41 (49%) | 0.019* | |
| III + IV | 45 (70%) | 43 (51%) | ||
| Histologic grade | ||||
| 1 | 38 (59%) | 46 (55%) | 0.58 | |
| 2 + 3 | 26 (41%) | 38 (45%) | ||
| Vascular invasion | ||||
| Absent | 53 (83%) | 71 (85%) | 0.78 | |
| Present | 11 (17%) | 13 (15%) | ||
| Perineural invasion | ||||
| Absent | 31 (48%) | 50 (60%) | 0.18 | |
| Present | 33 (52%) | 34 (40%) | ||
| Extracapsular extension | ||||
| Absent | 43 (67%) | 68 (81%) | 0.06 | |
| Present | 21 (33%) | 16 (19%) | ||
| Surgical margin | ||||
| Negative | 58 (91%) | 79 (94%) | 0.43 | |
| Positive | 6 (9%) | 5 (6%) | ||
| Smoking history | ||||
| Absent | 12 (19%) | 14 (17%) | 0.74 | |
| Present | 52 (81%) | 70 (83%) | ||
| Alcohol history | ||||
| Absent | 11 (17%) | 19 (23%) | 0.42 | |
| Present | 53 (83%) | 65 (77%) | ||
| Betel-nut chewing history | ||||
| Absent | 11 (17%) | 25 (30%) | 0.08 | |
| Present | 53 (83%) | 59 (70%) | ||
AJCC, American Joint Committee on Cancer. *Statistically significant