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Corneal vascularizationa
| Test substance | No. of corneas
|
|
|---|---|---|
| Vascularized | Unvascularized | |
| Fisp12 | 7 | 1 |
| bFGF | 4 | 0 |
| Fisp12 buffer | 0 | 4 |
| Fisp12 plus anti-Fisp12 | 0 | 4 |
Hydron pellets were formulated with purified Fisp12 (100 ng), Fisp12 storage buffer, bFGF (3 ng), or Fisp12 preincubated with anti-Fisp12 antibodies (2.3 μg) and implanted into rat corneas. Corneal vascularization was scored 7 days after implantation.
