Schematic illustrating source–object–detector geometry. The field-of-view size is the diameter (“D”) of the sample holder (tube). The nominal voxel size is the field-of-view divided by the matrix size of the detector array. Thus, using the smallest sample holder that will contain your samples is recommended to give the best resolution, that is, smallest voxel size. Similarly, selecting a larger matrix size will improve resolution, although at the cost of larger file sizes and slower reconstruction times