. 2021 Sep 1;129(9):097002. doi: 10.1289/EHP9200

Table 3.

Differences in glucose concentrations in individuals with high PFHxS levels ( $\geq 2.0 ng / dL$ ) vs. individuals with low PFHxS levels during a 2-h oral glucose tolerance test in $n = 310$ overweight and obese adolescents recruited from Southern California between 2001 and 2012 (SOLAR cohort) and in $n = 135$ young adults recruited from Southern California between 2014 and 2018 (CHS cohort).

Sex	Glucose (mg/dL at each time point)	SOLAR					CHS
Sex	Glucose (mg/dL at each time point)	Prepuberty (Tanner 1)	Early puberty (Tanner 2)	Puberty (Tanner 3)	Late puberty (Tanner 4)	Postpuberty (Tanner 5)	Young adults
		36/143^a	79/139^a	71/75^a	126/105^a	236/176^a	60/76^a
Female	Fasting	$- 2$ ( $- 16$ , 12)	2 ( $- 7$ , 11)	1 ( $- 9$ , 12)	4 ( $- 6$ , 14)	6 ( $- 8$ , 19)	3 ( $- 17$ , 23)
	30-min	13 (0, 27)	4 ( $- 5$ , 13)	6 ( $- 5$ , 16)	8 ( $- 3$ , 18)	11 ( $- 2$ , 25)	2 ( $- 18$ , 22)
	60-min	$- 4$ ( $- 18$ , 10)	6 ( $- 3$ , 15)	3 ( $- 8$ , 13)	21 (10, 31)	25 (12, 39)	26 (6, 46)
	2-h	$- 2$ ( $- 15$ , 12)	4 ( $- 5$ , 13)	$- 2$ ( $- 12$ , 8)	12 (1, 22)	15 (1, 28)	19 ( $- 1$ , 39)
Male	Fasting	$- 7$ ( $- 15$ , 0)	$- 2$ ( $- 12$ , 7)	0 ( $- 12$ , 13)	0 ( $- 13$ , 13)	$- 5$ ( $- 20$ , 11)	1 ( $- 12$ , 13)
	30-min	$- 4$ ( $- 12$ , 4)	$- 10$ ( $- 20$ , 0)	$- 8$ ( $- 20$ , 5)	$- 9$ ( $- 21$ , 4)	$- 25$ ( $- 41$ , $- 9$ )	1 ( $- 12$ , 15)
	60-min	$- 3$ ( $- 11$ , 5)	$- 1$ ( $- 11$ , 8)	$- 7$ ( $- 19$ , 5)	$- 9$ ( $- 21$ , 4)	$- 25$ ( $- 40$ , $- 9$ )	3 ( $- 10$ , 17)
	2-h	$- 7$ ( $- 15$ , 0)	$- 6$ ( $- 15$ , 4)	$- 4$ ( $- 16$ , 8)	$- 13$ ( $- 26$ , 0)	$- 10$ ( $- 26$ , 6)	$- 2$ ( $- 15$ , 12)

Note: Results are displayed as the difference and 95% confidence interval between individuals with high ( $\geq 2.0 ng / dL$ ) and low PFHxS levels at baseline. Estimates were calculated at the median age and BMI for each Tanner stage using linear mixed effects models. Estimates were corrected for socioeconomic status, and for the SOLAR study, recruitment wave. BMI, body mass index; CHS, Children’s Health Study; PFHxS, perfluorohexane sulfonic acid; SOLAR, Study of Latino Adolescents at Risk of Type 2 Diabetes.

^{^a}

Number of observations per developmental stage for females and males ( $n$ female observations/ $n$ male observations).