TABLE 1.
Patient characteristics
| Parameter | Number of patients (N = 72) |
|---|---|
| Median age, years (range) | 76 (30‐97) |
| Male | 29 (52%) |
| Female | 43 (48%) |
| Paraprotein type | |
| IgG | 30 (42%) |
| IgA | 22 (31%) |
| IgD | 1 (1%) |
| LCD | 19 (26%) |
| International staging system | |
| I | 16 (22%) |
| II | 15 (21%) |
| III | 41 (57%) |
| Elevated LDH level (>ULN) | 26 (36%) |
| Elevated β2‐MG level (≥3.5 mg/L) | 47 (65%) |
| Cytogenetic abnormalities | |
| t(4;14) | 7 (10%) |
| del(17p) | 9 (13%) |
| t(14;16) | 2 (3%) |
| t(11;14) | 24 (32%) |
| del(13q) | 37 (51%) |
| 1q21 gains | 36 (50%) |
| Lymphoplasmacytoid morphology | 12 (16%) |
Abbreviations: LCD, light chain disease; LDH, lactate dehydrogenase; ULN, upper limit of normal; β2‐MG, β2‐microgulobulin.