Table 4.

Novel methodological aspects and findings

	Novel methodological aspects	Novel findings
Lung ultrasound image acquisition	Use of a simplified 4-zone imaging protocol.	Among patients with acute heart failure (AHF) B-lines on lung ultrasound can be detected and quantified with a simplified 4-zone protocol in the majority of patients.
Lung ultrasound image analysis	Use of offline image analysis at a core laboratory Use of temporal blinding
Outcome analysis	Assessment of inpatient events	B-lines detected and quantified by the simplified protocol in patients hospitalized for AHF provided prognostic information regarding short-term in-hospital and longer term adverse events.
Data analysis		There was a time-varying association between B-line number and long term outcomes, such that the association was strongest during the initial part of follow-up and seemed to attenuate beyond 90 days post-discharge.