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Alignment of NBD1 regions from MRP family members. An alignment of the NBD1 segments from each of the indicated ABC transporter proteins is shown. The numbers refer to the respective positions along the polypeptide chain, and residues that are identical in at least three of the five selected proteins are boxed. The conserved structural motifs present in all ABC transporters are indicated by the heavy lines, and the sites of mutations in Yor1p NBD1 are denoted by arrows.
