TABLE 1.
rBC2LCN‐precipitated membrane glycoproteins in pancreatic ductal adenocarcinoma (PDAC) identified by LC‐MS/MS analysis
No. | Protein name | Gene | Unique peptides | N‐glycosylation sitesa | O‐glycosylation sitesb |
---|---|---|---|---|---|
1 | Integrin beta 1 | ITGB1 | 7 | 12 | 13 |
2 | Lysosome‐associated membrane glycoprotein 1 | LAMP1 | 3 | 18 | 7 |
3 | Prostate stem cell antigen | PSCA | 3 | 3 | 0 |
4 | 4F2 cell surface antigen heavy chain | SLC3A2 | 3 | 4 | 1 |
5 | Spectrin beta chain, nonerythrocytic 1 | SPTBN1 | 3 | 6 | 134 |
6 | CD44 antigen | CD44 | 2 | 11 | 145 |
7 | CD63 antigen | CD63 | 2 | 3 | 3 |
8 | Carcinoembryonic antigen‐related cell adhesion molecule 5 | CEA/CEACAM5 | 2 | 29 | 2 |
9 | Carcinoembryonic antigen‐related cell adhesion molecule 6 | CEACAM6 | 2 | 12 | 2 |
10 | Glucose transporter type 1 | GLUT1 | 2 | 2 | 1 |
11 | Transferrin receptor protein 1 | TFRC | 2 | 5 | 11 |
12 | Mucin 16 | MUC16 | 2 | 117 | 4876 |
The number of N‐glycosylation sites was predicted by the NetNGlyc 1.0 server (http://www.cbs.dtu.dk/services/NetNGlyc/).
The number of O‐glycosylation sites was predicted by the NetOGlyc 4.0 server (http://www.cbs.dtu.dk/services/NetOGlyc/).