TABLE 1.
Study cohort n = 312 | n | % |
---|---|---|
Gender | ||
Female | 118 | 37.8 |
Male | 194 | 62.2 |
Age at diagnosis (y) | ||
Mean | 50.0 | – |
Median | 51.5 | – |
Range | 18‐75 | – |
Preoperative KPS score | ||
>70 | 206 | 66.0 |
≤70 | 106 | 34.0 |
Extent of resection | ||
GTR | 165 | 52.9 |
STR | 127 | 40.7 |
PR | 20 | 6.4 |
TERT promoter (n = 167) | ||
Mutant | 93 | 55.7 |
WT | 74 | 44.3 |
MGMTp | ||
Methylated (mean ≥ 12%) | 130 | 41.7 |
Unmethylated (mean < 12%) | 182 | 58.3 |
MGMT protein | ||
<30% | 147 | 47.1 |
≥30% | 165 | 52.9 |
PFS (mo) | ||
Median | 9.5 | |
Range | 1.0‐75.0 | |
OS (mo) | ||
Median | 20.0 | |
Range | 1.0‐80.0 |
Abbreviations: GTR, gross total removal; KPS, Karnofsky Performance Status; OS, overall survival; PFS, progression‐free survival; PR, partial removal; STR, subtotal removal.