Fig. 11. Unimolecular channels (A) CLC chloride channel with key helical domains (PDB: 1KPL) and CLC mimic;⁹⁹ (B) Multiblock amphiphile by Kinbara with anisotropic ligand response¹⁰⁰ (C) Gramicidin-modified pillararenes by Chen¹⁰³ (D) Rigid rod ion channels reported by Zhu and co-workers.¹⁰⁴.