Table 1.
Admission Year | National Vaccination Coverage Rate | Suspected Cases | Probable Cases | Confirmed Bacterial Meningitis Cases by Culture and PCR | ||||
---|---|---|---|---|---|---|---|---|
Confirmed Cases | Streptococcus pneumoniae | Haemophilus influenzae | Neisseria meningitidis | |||||
Pentavalent | PCV10 | |||||||
2010 | 97 | - | 268 | 43 (16%) | 4 (9%) | 4 (100%) | 0 (0) | 0 (0) |
2011 | 95 | - | 292 | 58 (20%) | 13 (22%) | 13 (100%) | 0 (0) | 0 (0) |
2012 | 91 | - | 490 | 80 (16%) | 34 (43%) | 29 (85%) | 3 (9%) | 2 (6%) |
2013 | 93 | 29a | 583 | 91 (16%) | 57 (63%) | 42 (74%) | 5 (9%) | 10 (18%) |
2014 | 92 | 88 | 521 | 78 (15%) | 41 (53%) | 20 (49%) | 9 (22%) | 12 (29%) |
2015 | 90 | 81 | 500 | 64 (13%) | 29 (45%) | 11 (38%) | 7 (24%) | 11 (38%) |
2016 | 99 | 98 | 471 | 65 (14%) | 19 (29%) | 11 (58%) | 5 (26%) | 3 (16%) |
2017 | 94 | 94 | 245 | 35 (14%) | 12 (34%) | 9 (75%) | 1 (8%) | 2 (17%) |
2018 | 90 | 90 | 239 | 46 (19%) | 8 (17%) | 5 (63%) | 1 (13%) | 2 (25%) |
2019 | 88 | 89 | 202 | 38 (19%) | 4 (11%) | 4 (100%) | 0 (0) | 0 (0) |
Total | - | - | 3811 | 598 | 221 | 148 | 31 | 42 |
Abbreviations: PCR, polymerase chain reaction; PCV10, 10-valent pneumococcal conjugate vaccine; UTH, University Teaching Hospital.
NOTES: (1) PCV10 introduction July 2013. National Vaccination Coverage Rate (percentage) reference: Ministry of Health of Zambia, April 2020, Expanded Programme on Immunisation. M. Silitongo, February 2019, Unpublished data. (2) Pentavalent: The 5-in-1 vaccine giving protection against diphtheria, tetanus, pertussis, polio, and Hib. (3) PCV10: The 10-valent pneumococcal conjugate vaccine giving protection against pneumococal diseases caused by 10 serotypes (1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F, 23F).
aYear PCV10 was introduced.