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. 2021 Sep 1;224(Suppl 3):S275–S284. doi: 10.1093/infdis/jiab193

Table 1.

National Vaccination Coverage Rate and Year of Admission of Children <5 Years With Suspected Probable and Confirmed Bacterial Meningitis by Culture and/or PCR at the UTH Children’s Hospital, 2010–2019

Admission Year National Vaccination Coverage Rate Suspected Cases Probable Cases Confirmed Bacterial Meningitis Cases by Culture and PCR
Confirmed Cases Streptococcus pneumoniae Haemophilus influenzae Neisseria meningitidis
Pentavalent PCV10
2010 97 - 268 43 (16%) 4 (9%) 4 (100%) 0 (0) 0 (0)
2011 95 - 292 58 (20%) 13 (22%) 13 (100%) 0 (0) 0 (0)
2012 91 - 490 80 (16%) 34 (43%) 29 (85%) 3 (9%) 2 (6%)
2013 93 29a 583 91 (16%) 57 (63%) 42 (74%) 5 (9%) 10 (18%)
2014 92 88 521 78 (15%) 41 (53%) 20 (49%) 9 (22%) 12 (29%)
2015 90 81 500 64 (13%) 29 (45%) 11 (38%) 7 (24%) 11 (38%)
2016 99 98 471 65 (14%) 19 (29%) 11 (58%) 5 (26%) 3 (16%)
2017 94 94 245 35 (14%) 12 (34%) 9 (75%) 1 (8%) 2 (17%)
2018 90 90 239 46 (19%) 8 (17%) 5 (63%) 1 (13%) 2 (25%)
2019 88 89 202 38 (19%) 4 (11%) 4 (100%) 0 (0) 0 (0)
Total - - 3811 598 221 148 31 42

Abbreviations: PCR, polymerase chain reaction; PCV10, 10-valent pneumococcal conjugate vaccine; UTH, University Teaching Hospital.

NOTES: (1) PCV10 introduction July 2013. National Vaccination Coverage Rate (percentage) reference: Ministry of Health of Zambia, April 2020, Expanded Programme on Immunisation. M. Silitongo, February 2019, Unpublished data. (2) Pentavalent: The 5-in-1 vaccine giving protection against diphtheria, tetanus, pertussis, polio, and Hib. (3) PCV10: The 10-valent pneumococcal conjugate vaccine giving protection against pneumococal diseases caused by 10 serotypes (1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F, 23F).

aYear PCV10 was introduced.