Table 3.
Streptococcus pneumoniae Serotypes Detected in Children <5 Years in the Pre- and Postvaccination Periods at the UTH Children’s Hospital, 2010–2019
| Serotypes | Prevaccination Period (2010–2012) | Vaccination Year (2013) | Postvaccination Period (2014–2019) | Total |
|---|---|---|---|---|
| PCV10 Serotypes = 36% (54 of 148) | ||||
| 1 | 9 | 7 | 5 | 21 |
| 4 | 2 | 2 | 0 | 4 |
| 5 | 0 | 0 | 1 | 1 |
| 6B | 1 | 3 | 0 | 4 |
| 7F | 1 | 0 | 0 | 1 |
| 14 | 0 | 2 | 2 | 4 |
| 18C | 2 | 2 | 0 | 4 |
| 19F | 2 | 4 | 1 | 7 |
| 23F | 3 | 3 | 2 | 8 |
| Total | 20 | 23 | 11 | 54 |
| PCV13 Serotypes = 16% (23 of 148) | ||||
| 3 | 1 | 1 | 1 | 3 |
| 6A | 1 | 1 | 0 | 2 |
| 6A/6B | 1 | 2 | 13 | 16 |
| 19A | 1 | 0 | 1 | 2 |
| Total | 4 | 4 | 15 | 23 |
| Nonvaccine Serotypes = 39% (57 of 148) | ||||
| 8 | 0 | 0 | 1 | 1 |
| 9V/9A | 0 | 0 | 2 | 2 |
| 10A/B | 1 | 0 | 0 | 1 |
| 10F/10C/33C | 1 | 0 | 0 | 1 |
| 15C | 3 | 0 | 0 | 3 |
| 18F | 1 | 3 | 0 | 4 |
| 18A/18B/18C/18F | 0 | 2 | 1 | 3 |
| 19B/F | 3 | 0 | 0 | 3 |
| 46 | 7 | 1 | 0 | 8 |
| NEG38 | 3 | 8 | 20 | 31 |
| Total | 19 | 14 | 24 | 57 |
| Insufficient DNA—Unable to Obtain Serotype = 9% (14 of 148) | ||||
| Total | 4 | 4 | 6 | 14 |
| Overall total | 47 | 45 | 56 | 148 |
Abbreviations: DNA, deoxyribonucleic acid; UTH, University Teaching Hospital.
NOTES: (1) PCV10: The 10-valent pneumococcal conjugate vaccine giving protection against pneumococal diseases caused by 10 serotypes (1, 4, 5, 6B, 7F, 9V, 14, 18C, 19F, 23F). (2) PCV13: Pneumococcal conjugate vaccine with purified capsular polysaccharide of 13 serotypes of Spn (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 19A, 19F, 18C, and 23F). (3) Nonvaccine serotype: Serotypes not covered by PCV10 and/or PCV13.