Table 3. Determination of antigenic sites for the mAbs.
Antibody | Antigenic Site | Codon Change | Amino Acid Change | Amino Acid Position * |
---|---|---|---|---|
NP-19-9 | III | TCA→ CCA | Ser(S)→ Pro(P) | 331 |
NP-19-35 | Unknown | GTG→ GAG | Val(V)→ Glu(E) | 210 |
GAG→ GAT | Glu(E)→ Asp(D) | 413 | ||
11B6 | II | GGA→ GTA | Gly(G)→ Val(V) | 34 |
GGA→ GAA | Gly(G)→ Glu(E) | 34 | ||
GGA→AGA | Gly(G)→ Arg(R) | 34 |
* Amino acid position refers to the position number (except for the signal peptide) of the rabies virus G-protein.