Table 3. SNPs in 3 novel loci associated with thoracic aortic aneurysm.

SNP	Chr:BP	Allele	Nearest Gene	Type	MAF (%)	OR (95% CI)	P-value
rs149014140	10:68,863,297	A/G	CTNNA3	Intronic	0.78	4.268 (2.57–7.07)	1.82x10-8
rs148927240	14:52,239,510	G/A	FRMD6	Intergenic	0.71	4.23 (2.55–7.01)	2.19x10-8
rs78851735	18:74,774,680	C/T	MBP	Intronic	0.98	3.446 (2.22–5.35)	3.79x10-8

CTNNA3, FRMD6 and MBP are novel TAA-associated loci identified in the present study (bold faced). Chr:BP denotes the chromosome location and NCBI Build 37 SNP physical position. MAF, minor allele frequency; OR, odds ratio.