Table 1.
Changes in each item of Menopause Rating Scale II score over time (n=70)
| MRS-II parameters | Baseline | Week 4 | Week 8 | Week 12 | Percentage difference baseline to 12th week | P* |
|---|---|---|---|---|---|---|
| Somatic subscale | ||||||
| Joint muscular discomfort | 2.5 (2.2-2.7) | 1.8 (1.6-2.1) | 1.3 (1.1-1.5) | 0.8 (0.5-1.0) | 68.00 | <0.001 |
| Sleep problems | 2.7 (2.5-2.9) | 2.3 (2.0-2.5) | 1.7 (1.5-1.9) | 0.8 (0.6-1.0) | 70.37 | <0.001 |
| Heart discomfort | 2.8 (2.6-3.1) | 2.3 (2.0-2.5) | 1.6 (1.3-1.8) | 0.8 (0.5-1.0) | 71.43 | <0.001 |
| Hot flushes | 2.8 (2.6-3.0) | 2.2 (2.0-2.4) | 1.5 (1.3-1.7) | 0.7 (0.5-0.9) | 75.00 | <0.001 |
| Urogenital subscale | ||||||
| Dryness of vagina | 1.9 (1.7-2.1) | 1.6 (1.3-1.8) | 1.2 (1.0-1.5) | 0.8 (0.5-1.0) | 57.89 | <0.001 |
| Bladder problems | 2.1 (1.9-2.4) | 1.8 (1.5-2.0) | 1.3 (1.1-1.5) | 0.9 (0.6-1.1) | 57.14 | <0.001 |
| Sexual problems | 1.9 (1.6-2.1) | 1.6 (1.4-1.8) | 1.2 (1.0-1.4) | 0.7 (0.5-0.9) | 63.16 | <0.001 |
| Psychological subscale | ||||||
| Physical and mental exhaustion | 2.4 (2.2-2.6) | 1.9 (1.7-2.1) | 1.4 (1.2-1.6) | 0.8 (0.6-1.0) | 66.67 | <0.001 |
| Anxiety | 2.4 (2.1-2.6) | 1.9 (1.6-2.1) | 1.3 (1.0-1.5) | 0.8 (0.6-1.0) | 66.67 | <0.001 |
| Irritability | 2.6 (2.4-2.9) | 1.9 (1.7-2.1) | 1.4 (1.2-1.6) | 0.9 (0.7-1.1) | 65.38 | <0.001 |
| Depressive mood | 2.6 (2.4-2.8) | 2.1 (1.9-2.3) | 1.4 (1.2-1.6) | 0.7 (0.5-0.9) | 73.08 | <0.001 |
*Comparison between results at baseline and 12 weeks. The data are represented by mean (95% CI). ANOVA was performed. MRS: Menopause Rating Scale, CI: Confidence interval, ANOVA: Analysis of variance