Skip to main content
. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Kidney Int. 2019 Nov 28;97(5):966–979. doi: 10.1016/j.kint.2019.11.013

Figure 3. NGAL production (mRNA) occurs predominantly in the liver after sham (surgery alone}, ischemic acute kidney injury (AKI) and bilateral nephrectomy (BNx), and liver NGAL mRNA is reduced in IL-6−/− mice.

Figure 3.

mRNA NGAL levels were determined in the (A-C) liver, (D, E) kidney, (F-H) lung, and (I-K) spleen in normal (unmanipulated) mice, and 4 and 24 hours after sham, AKI or BNx in wild type (WT) and IL-6−/− mice. N=3 to 12 mice per group from 3 experiments. Results are expressed as mean ±SEM and analyzed by t test: WT versus IL-6−/− at the same time point (indicated above the bar) and versus normal WT (indicated below the bar: *P<0.05; **P<0.01, ***P < 0.0001).