Figure 1.

SNHG12 is upregulated in AS. (a) The SNHG12 level in AS patients’ sera (n = 30) and normal sera (n = 30) was determined by RT-qPCR. HUVECs were treated with various concentrations of ox‑LDL (0, 10, 30, and 50 µg/ml) for 24 h, and (b) cell proliferation was examined using CCK-8, (c) SNHG12 expression was determined by RT-qPCR. (d) HUVECs were treated with 50 µg/ml ox-LDL for 0, 24, 48 and 72 h, and SNHG12 expression was determined by RT-qPCR. (e) HUVECs were exposed to 10 µg/ml, 30 µg/ml, or 50 µg/ml ox-LDL, respectively, for 0, 24, 48 and 72 h, and cell proliferation was detected by CCK-8. *P < 0.05, **P < 0.01, ***P < 0.001