Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Internalization of WT avelumab compared with its anti–PD-L1 binding–deficient variant (R99K) and FcγR binding–deficient variant (N297A) in total human monocytes and granulocytes. Internalization in (a) total monocytes and (b) granulocytes from a representative donor is shown. Results were similar in other donors (data not shown). Error bars represent standard deviations of replicate assays from the same donor. Anti–PD-L1, anti–programmed death ligand 1; WT, wild-type
