Table 3.

Estimated glomerular filtration rate slope before and after the administration of sodium–glucose cotransporter 2 inhibitors was adjusted by age, sex, change in glycated hemoglobin and change in body mass index

Model	Before SGLT2is	After SGLT2is	P‐value
Model 1	−2.65 ± 0.58	−0.06 ± 0.20	<0.001
Model 2	−2.82 ± 0.61	−0.08 ± 0.21	<0.001
Model 3	−2.42 ± 0.77	−0.46 ± 0.24	0.017

Data presented as adjusted average ± standard error. Model 1 was adjusted by age and sex. Model 2 was adjusted by age, sex and change in glycated hemoglobin. Model 3 was adjusted by age, sex, change in glycated hemoglobin and change in body mass index. Even after estimated glomerular filtration rate slope was adjusted by all factors, estimated glomerular filtration slope was significantly slowed after the starting of sodium–glucose cotransporter 2 inhibitors (SGLT2is). Linear mixed model.