Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 23;129(6):631–646. doi: 10.1161/CIRCRESAHA.121.319117

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 American Heart Association, Inc.

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

PMC Copyright notice

Figure 6. — Pathway enrichment analysis of coronavirus disease 2019 (COVID-19) platelet transcriptome suggests programmed cell death. Platelets from patients with COVID-19 (n=10) and patients with myocardial infarction (ST-segment–elevation myocardial infarction [n=10], non–ST-segment–elevation myocardial infarction [n=10]) without COVID-19 were isolated and sequenced. Pathway enrichment analyses, with the respective P values were generated in https://metascape.org/ using the fold changes from the RNAseq (RNA sequencing) data of the highest, statistically significant, 40 upregulated, and 40 downregulated genes. Fold changes of the sequencing results are included in Table VII in the Data Supplement. IFN indicates interferon. MYC indicates myelocytomatosis; PDGFRB, platelet-derived growth factor receptor beta; and PM, plasma membrane.