Figure 13.

Behavioral reentrainment occurs more quickly than pancreatic transcriptomic reentrainment. Double plotted behavioral actograms for normal circadian (NC) and chronic jetlag (CJ) mice utilizing the ClockLab software. Behavioral activity is a normalized average of seven mice (NC: n = 3 males/n = 4 females and CJ: n = 4 males/n = 3 females) in each condition and manually checked for masking effects. The initial light-dark (LD) cycle is shown for each condition in a bar above each plot, with white indicating light and black indicating darkness. The arrow indicates the onset of darkness on day one of normalization. Reentrainment occurred behaviorally when activity became vertically aligned with the LD cycle. Following normalization after CJ conditions, reentrainment occurred within 2−3 days.