Table 2.
Stroop Color and Word Test | Young Adults | Older Adults | P Value (Effect Size) |
---|---|---|---|
MAP, mmHg | |||
Control | |||
Baseline | 90 ± 13 | 94 ± 11 | 0.152 (0.27) |
Stroop | 92 ± 12 | 98 ± 13 | 0.051 (0.50) |
Indomethacin | |||
Baseline | 91 ± 12 | 96 ± 13 | 0.121 (0.36) |
Stroop | 92 ± 13 | 98 ± 15 | 0.093 (0.41) |
PP, mmHg | |||
Control | |||
Baseline | 74 ± 16 | 73 ± 12 | 0.445 (0.04) |
Stroop | 76 ± 18 | 75 ± 11 | 0.415 (0.06) |
Indomethacin | |||
Baseline | 73 ± 14 | 76 ± 11 | 0.208 (0.25) |
Stroop | 74 ± 14 | 76 ± 13 | 0.379 (0.09) |
HR, beats/min | |||
Control | |||
Baseline | 60 ± 7 | 59 ± 8 | 0.231 (0.22) |
Stroop | 68 ± 10 | 67 ± 10 | 0.387 (0.09) |
Indomethacin | |||
Baseline | 55 ± 8 | 55 ± 8 | 0.468 (0.02) |
Stroop | 60 ± 9 | 62 ± 9 | 0.269 (0.19) |
MCAv, cm/s | |||
Control | |||
Baseline | 60 ± 13 | 50 ± 16 | 0.017 (0.66) |
Stroop | 63 ± 14 | 53 ± 17 | 0.027 (0.60) |
Indomethacin | |||
Baseline | 42 ± 8* | 37 ± 9* | 0.016 (0.67) |
Stroop | 44 ± 9* | 38 ± 9* | 0.027 (0.60) |
CVCi, cm/s/mmHg | |||
Control | |||
Baseline | 0.68 ± 0.17 | 0.54 ± 0.18 | 0.007 (0.78) |
Stroop | 0.70 ± 0.19 | 0.55 ± 0.18 | 0.007 (0.77) |
Indomethacin | |||
Baseline | 0.47 ± 0.11* | 0.39 ± 0.12* | 0.012 (0.70) |
Stroop | 0.48 ± 0.12* | 0.40 ± 0.12* | 0.015 (0.68) |
Cerebral PI, AU | |||
Control | |||
Baseline | 0.71 ± 0.12 | 0.76 ± 0.10 | 0.054 (0.50) |
Stroop | 0.70 ± 0.12 | 0.74 ± 0.11 | 0.126 (0.35) |
Indomethacin | |||
Baseline | 0.86 ± 0.16* | 0.89 ± 0.13* | 0.223 (0.23) |
Stroop | 0.87 ± 0.17* | 0.89 ± 0.14* | 0.416 (0.08) |
Values are expressed as means ± SD. Cerebral PI, cerebral pulsatility index; CVCi, cerebrovascular conductance index; HR, heart rate; MAP, mean arterial blood pressure; MCAv, middle cerebral artery blood velocity; PP, pulse pressure. P value in bold indicates a significant difference between young and older adults at baseline or in response to the Stroop color and word test (independent-samples t test or Wilcoxon rank-sum test). *P < 0.05 significantly different vs. control at baseline or in response to the Stroop color and word test (dependent-samples t test or Wilcoxon signed-rank test).