Table 1.
All patients | Twice-weekly HD | Thrice-weekly HD | P value | |
---|---|---|---|---|
No. of patients | 144 | 54 | 90 | |
Gender M:F | 75:69 | 26:28 | 49:41 | |
Anuric status, n (%) | 133 (92.4) | 44 (81.5) | 89 (98.9) | |
Age years | 60.2 ± 13.3 | 61.9 ± 14.6 | 59.2 ± 12.4 | 0.243 |
HD vintage years | 9.9 ± 6.2 | 7.7 ± 5.7 | 11.3 ± 6.1 | 0.001 |
Diabetic status, n (%) | 37(25.7) | 13(24.1) | 24(26.7) | |
Body surface area m2 | 1.64 ± 0.18 | 1.61 ± 0.16 | 1.66 ± 0.19 | 0.079 |
Body mass index kg/m2 | 22.0 ± 3.2 | 21.4 ± 2.8 | 22.4 ± 3.4 | 0.077 |
Systolic BP mmHg | 143.9 ± 22.7 | 150.1 ± 18.1 | 140.2 ± 24.4 | 0.011 |
Diastolic BP mmHg | 75.2 ± 14.1 | 76.7 ± 11.6 | 74.4 ± 15.4 | 0.339 |
Blood urea nitrogen mmol/L | 27.8 ± 7.5 | 32.2 ± 7.9 | 25.2 ± 5.9 | 0.000 |
Serum creatinine umol/L | 1043.3 ± 275.5 | 1131.3 ± 279.2 | 990.6 ± 260.8 | 0.003 |
SpKt/V | 1.94 ± 0.39 | 2.11 ± 0.37 | 1.84 ± 0.36 | 0.000 |
URR % | 78.3 ± 7.8 | 81.0 ± 5.2 | 76.7 ± 8.6 | 0.001 |
Weekly SpKt/V | 5.03 ± 1.15 | 4.23 ± 0.74 | 5.52 ± 1.08 | 0.000 |
HD session time hours | 4.19 ± 0.45 | 4.44 ± 0.47 | 4.05 ± 0.38 | 0.000 |
UF rate mL/kg/hr | 13.08 ± 4.00 | 13.01 ± 4.46 | 13.11 ± 3.72 | 0.887 |
Dry weight kg | 57.1 ± 11.2 | 54.7 ± 9.9 | 58.5 ± 11.7 | 0.051 |
Hemoglobin g/L | 109.1 ± 16.9 | 107.2 ± 14.5 | 110.3 ± 18.2 | 0.295 |
Serum albumin g/l | 39.4 ± 3.3 | 39.7 ± 4.2 | 39.2 ± 2.6 | 0.386 |
HsCRP mg/l | 4.6 ± 9.0 | 4.6 ± 10.0 | 4.7 ± 8.4 | 0.929 |
Calcium mmol/L | 2.29 ± 0.29 | 2.25 ± 0.27 | 2.32 ± 0.30 | 0.193 |
Phosphorus mmol/L | 1.99 ± 0.55 | 2.00 ± 0.54 | 1.99 ± 0.56 | 0.990 |
iPTH pg/ml | 459.2 ± 407.0 | 393.0 ± 434.6 | 498.9 ± 386.5 | 0.131 |
Cholesterol mmol/L | 3.94 ± 0.99 | 3.96 ± 1.03 | 3.93 ± 0.98 | 0.858 |
Triglyceride mmol/L | 1.72 ± 1.68 | 1.37 ± 0.69 | 1.93 ± 2.03 | 0.053 |
BNP pg/ml | 264.5(14-4995) | 346.5(27-4995) | 210(14-4995) | |
Log BNP pg/ml | 2.41 ± 0.47 | 2.54 ± 0.41 | 2.33 ± 0.49 | 0.010 |
NOTE. Data are expressed as mean ± SD, P values result from comparisons of baseline values of the two groups divided by HD frequency.
Abbreviations: HD: hemodialysis; BP: blood pressure; SpKt/V: single-pool Kt/V; URR: urea reduction ratio; UF: ultrafiltration; HsCRP: hypersensitive C reactive protein; iPTH: intact parathyroidism hormone; BNP: B-type natriuretic peptide; Log BNP: log-transformed B-type natriuretic peptide.