Table 1.

List of web servers used in the text.

Webserver	Purpose	URL of webserver	Reference
ExPASy	Physico-chemical predictions	https://web.expasy.org/protscale/	(Wilkins et al., 1999)
EMBOSS	Hydrophobic moment prediction	https://www.bioinformatics.nl/cgi-bin/emboss/hmoment	(Carver & Bleasby, 2003)
Composition profiler	Flexibility and hydrophilicity prediction	http://www.cprofiler.org/	(Vacic et al., 2007)
IUPred2A, PrDOS, ANCHOR2	Disorder prediction	http://iupred2a.elte.hu http://prdos.hgc.jp/cgi-bin/top.cgi http://anchor.elte.hu/	(Mészáros et al., 2018; Ishida & Kinoshita, 2007)
CIDER	Conformational disorder prediction	http://pappulab.wustl.edu/CIDER/analysis/	(Holehouse et al., 2017)
RaptorX	Secondary structure prediction	http://raptorx.uchicago.edu/	(Wang et al., 2016)
NetSurfP	Surface accessibility, secondary structure, and disorder prediction	https://services.healthtech.dtu.dk/service.php?NetSurfP-2.0	(Klausen et al., 2019)
I-TASSER	3D structure prediction	https://zhanglab.ccmb.med.umich.edu/I-TASSER/	(Yang & Zhang, 2015)
PROCHECK, ERRAT, Verify-3D	3D structure validation	http://services.mbi.ucla.edu/SAVES/	(Colovos & Yeates, 1993; Laskowski et al., 1993; Eisenberg et al., 1997)
Ramachandran	3D structure validation	http://mordred.bioc.cam.ac.uk/_rapper/rampage.php	(Ramachandran et al., 1963)
PDB2PQR server	Electrostatic potential evaluation	https://server.poissonboltzmann.org/	(Dolinsky et al., 2004)
PPM server	Membrane interaction evaluation	https://opm.phar.umich.edu/ppm_server	(Lomize et al., 2012)
CELLPM Server	Membrane interaction evaluation	https://cellpm.org/cellpm_server	(Lomize & Pogozheva, 2018)
CPPred-FL	CPP prediction	http://server.malab.cn/CPPred-FL/	(Qiang et al., 2018)
SkipCPP-Pred	CPP prediction	http://server.malab.cn/SkipCPP-Pred/Index.html	(Wei et al., 2017a)
MLCPP	CPP prediction	http://www.thegleelab.org/MLCPP/	(Manavalan et al., 2018)
CPPred-RF	CPP prediction	http://server.malab.cn/CPPred-RF/	(Wei et al., 2017b)
CellPPD	CPP prediction	http://crdd.osdd.net/raghava/cellppd/	(Gautam et al., 2013)
Class I immunogenicity server	Immunogenicity prediction	http://tools.iedb.org/immunogenicity/	(Calis et al., 2013)
ProtLifePred server	Half-life prediction	http://protein-n-end-rule.leadhoster.com/	(Bachmair et al., 1986)