Figure 3.

Antibody (A) and T-cell (B) persistence after one dose of ChAdOx1 nCoV-19 vaccine

Datapoints represent individual participants and the solid line represents estimates from a linear regression model, with shaded areas showing the 95% CI. Antibody levels to SARS-CoV-2 Victoria/01/2020 spike measured by total IgG ELISA over 1 year after a single dose. Data are from 480 participants across COV001 and COV002 who received a standard dose of ChAdOx1 nCoV-19. Vaccine-induced T-cell responses against the SARS-CoV-2 spike insert were monitored up to day 182 in a cohort of 44 participants who received a single dose of ChAdOx1 nCoV-19. For participants who were excluded from these analyses due to positive PCR test result, second dose on trial, or external COVID-19 vaccination, no ELISA results or ELISpot results beyond the date of censoring were used. PBMCs=peripheral blood mononuclear cells. SFUs=spot-forming units