Table 3.

Manifestation scores for febuxostat vs placebo at baseline, days 1, 3, 5 and 7

Parameters	Placebo, mean (s.d.)	Febuxostat, mean (s.d.)	P a
Joint pain score
Baseline	2.87 (0.99)	2.89 (0.99)	0.932
day 1	2.01 (1.20)	1.93 (1.22)	0.601
day 3	1.09 (1.01)	0.97 (1.04)	0.383
day 5	0.51 (0.65)	0.67 (0.81)	0.319
day 7	0.13 (0.42)	0.26 (0.50)	0.057
Joint swelling score
Baseline	1.99 (0.88)	1.93 (0.87)	0.726
day 1	1.69 (0.93)	1.50 (0.96)	0.219
day 3	0.85 (0.79)	0.75 (0.76)	0.454
day 5	0.45 (0.63)	0.41 (0.55)	0.848
day 7	0.13 (0.34)	0.20 (0.47)	0.468
Joint tenderness score
Baseline	1.61 (0.49)	1.60 (0.55)	0.970
day 1	1.36 (0.57)	1.22 (0.65)	0.207
day 3	0.73 (0.59)	0.58 (0.58)	0.149
day 5	0.38 (0.49)	0.45 (0.53)	0.458
day 7	0.14 (0.38)	0.19 (0.43)	0.387
Joint erythema score
Baseline	1.46 (0.63)	1.40 (0.69)	0.704
day 1	1.14 (0.80)	1.00 (0.74)	0.288
day 3	0.46 (0.56)	0.38 (0.57)	0.283
day 5	0.26 (0.44)	0.30 (0.49)	0.659
day 7	0.10 (0.30)	0.15 (0.39)	0.550

^aCalculated from Mann–Whitney U test.