Figure 2. Bacterial composition of the cervicovaginal fluid based on Principal Coordinates Analysis (PCoA) groups and stratified by pregnancy outcome.

(A) Distribution of PCoA groups in the whole community based on delivery outcome for term birth and spontaneous preterm birth before 37 weeks’ gestation (sPTB37) in early samples (10–15⁺⁶ weeks). (B–D) Dynamics of PCoA groups during pregnancy as identified in the early and late (16–23⁺⁶ weeks) sampling times in relation to delivery outcome for the whole community (B), for White women (C), and Black women (D). Circles represents early samples, and crosses represent late samples. (A and B) Early samples term, n = 255, and sPTB37, n = 50; late samples term, n = 263, and sPTB37, n = 50. (C) White women early samples term, n = 184, and sPTB37, n = 23; late samples term, n = 190, and sPTB37, n = 28. (D) Black women early samples term, n = 51, and sPTB37, n = 16; late samples term, n = 52, and sPTB37, n = 13.