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. 2021 Jul 8;6(13):e140028. doi: 10.1172/jci.insight.140028

Figure 3. Public putatively peanut-specific CDR3β sequences are characterized by being closer to germline and exhibiting convergent recombination.

Figure 3

(A) Public putatively peanut-specific CDR3β sequences (ps-CDR3s) are closer to germline than private ps-CDR3s. Distribution of total, V-D, and D-J insertions of public and private ps-CDR3s (**P < 0.01, Mann-Whitney U test). (B) Public ps-CDR3s demonstrate more convergent recombination than private ps-CDR3s. Violin plots represent the number of unique nucleotide sequences responsible for each unique public and private ps-CDR3 (**P < 0.01, Mann-Whitney U test). (C) Convergence of public ps-CDR3s occurs in both germline (V gene) and nongermline (CDR3β) regions. Logo plots represent the probability of either specific gene segments (red) or CDR3β nucleotides (blue) to be encoding for their corresponding amino acid sequence.