Table 3.

MCA active and passive vessel tone (60 mmHg)

	1 Mo			3 Mo			7 Mo
	Air	E-cig0	E-cig18	Air	E-cig0	E-cig18	Air	E-cig0	E-cig18
Active OD, µm	82 ± 4	95 ± 4	109 ± 4*	129 ± 3	132 ± 7	147 ± 7	145 ± 5	157 ± 7	165 ± 8
Myogenic tone, %	48 ± 6	45 ± 4	41 ± 4	34 ± 1	36 ± 5	42 ± 2	32 ± 2	34 ± 3	30 ± 3
Passive ID, µm	116 ± 13	133 ± 9	133 ± 8	131 ± 3	140 ± 10	140 ± 12	137 ± 5	144 ± 8	149 ± 7
Passive OD, µm	140 ± 18	166 ± 9	171 ± 10	174 ± 4	184 ± 16	196 ± 13	194 ± 7	207 ± 11	210 ± 9
Passive WT, µm	12 ± 3	17 ± 2	19 ± 2	22 ± 1	22 ± 3	28 ± 2	28 ± 2	31 ± 2	31 ± 2
WLR	0.19 ± 0.03	0.26 ± 0.03	0.30 ± 0.04	0.33 ± 0.02	0.31 ± 0.03	0.42 ± 0.03	0.42 ± 0.04	0.44 ± 0.03	0.42 ± 0.02

Values are means ± SD. E-cig0, E-cig device without nicotine; E-cig18, E-cig device with 18 mg/mL nicotine; ID, inner diameter; OD, outer diameter; WLR, wall-to-lumen ratio; WT, wall thickness.

*P < 0.05 vs. control (air) within age group.