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. 2021 Jun 18;321(2):H318–H338. doi: 10.1152/ajpheart.00086.2021

Table 2.

Parameter values for simulating the five different disease scenarios described in the section Chronic Thromboembolic Pulmonary Hypertension

Case
Parameter Normotensive a b c d
k1la, g/cm⋅s2 2.5 × 106 2.5 × 106 2.5 × 106 2.5 × 106 2.5 × 106
k2la, 1/cm −15 −15 −20 −20 −10
k3la, g/cm⋅s2 6.4 × 104
6.4 × 104
8.0 × 104
(1.6 × 105)
8.0 × 104
(1.6 × 105)
2.0 × 105
(4.0 × 105)
k1sa, g/cm⋅s2 2.5 × 107 2.5 × 107 5.0 × 107 5.0 × 107 5.0 × 107
k2sa, 1/cm −15 −15 −20 −20 −20
k3sa, g/cm⋅s2 8.0 × 105
8.0 × 105
1.6 × 106
(1.6 × 107)
1.6 ×106
(1.6 ×107)
1.6 × 106
(1.6 × 107)
k lesion, g/(cm·s2) 6.4 × 105 8.0 × 105 8.0 × 105 2.0 × 106
Ztrm, g/cm4⋅s 1.0 × 105

1.0 × 105
1.0 × 106
(1.0 × 108)
1.0 × 107
(1.0 × 108)
1.0 × 108
(1.0 × 108)

k3 and Ztrm values are listed for vessels in both the unobstructed and obstructed pathways (in parentheses).