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. 2021 Aug 24;2021:9942152. doi: 10.1155/2021/9942152

Figure 8.

Figure 8

Schematic model of the PGC-1α/LXR pathways in mRTECs and the protective effect of MOR on PA or HG-induced lipid accumulation in mRTECs. MOR can activate the activities of ABCA1, ABCG1, and ApoE with PGC-1α as the central target to inhibit lipid accumulation in mRTECs.