Table 2.
Baseline cfDNA (ng·mL−1) | N (events) | HR | 95% CI | P value | |
---|---|---|---|---|---|
OS | < 100 | 36 (29) | 1 | 0.0355 | |
≥ 100 | 7 (7) | 2.48 | 1.06–5.77 | ||
< 26 | 24 (18) | 1 | 0.0407 | ||
≥ 26 | 19 (18) | 2.02 | 1.03–3.95 | ||
< 65 | 33 (26) | 1 | 0.0458 | ||
≥ 65 | 10 (10) | 2.12 | 1.01–4.45 | ||
< 26 | 24 (18) | 1 | 0.0534 | ||
26–100 | 12 (11) | 1.67 | 0.78–3.62 | 0.19 | |
≥ 100 | 7 (7) | 2.93 | 1.20–7.17 | 0.0188 | |
Log | 43(36) | 1.26 | 1.01–1.56 | 0.0371 | |
PFS | < 26 | 24 (22) | 1 | 0.1947 | |
≥ 26 | 19 (19) | 1.51 | 0.81–2.83 | ||
< 65 | 33 (31) | 1 | 0.4507 | ||
≥ 65 | 10 (10) | 1.32 | 0.64–2.71 | ||
< 100 | 36 (4) | 1 | 0.3683 | ||
≥ 100 | 7 (7) | 1.47 | 0.64–3.40 | ||
< 26 | 24 (22) | 1 | 0.4115 | ||
26–100 | 12 (12) | 1.45 | 0.71–2.94 | 0.311 | |
≥ 100 | 7 (7) | 1.66 | 0.69–4.00 | 0.2589 | |
log | 43 (41) | 1.2 | 0.97–1.49 | 0.0946 |