Table 1.
Data set ID | Location | Species | Age | Cell type | AML type | Treatment | Type of data | Reference |
---|---|---|---|---|---|---|---|---|
AML1 | https://www.stjuderesearch.org/site/data/AML1/ | Human | Paediatric and Adult |
Primary BM, PB |
M0‐M7 | None | Microarray | Ross et al. (2004) [119] |
GSE1159 | GEO | Human | Adult | Primary BM, PB | AML (M0 – M7) and healthy | None | Microarray | Valk et al. (2004) [42] |
GSE4119 | GEO | Human | Paediatric and Adult |
Primary BM, PB |
AMKL | None | Microarray | Bourquin et al. (2006) [120] |
GSE5258 | GEO | Human | Adult | Cell lines MCF7, HL60, ssMCF7, PC3, SKMEL5 | AML M2, Breast adenocarcinoma, prostate carcinoma, melanoma | 164 small molecules | Microarray | Lamb et al. (2006) [104] |
GSE17061 | GEO | Human | Unknown | Primary BM, PB | AML‐M0 | None | Microarray | Silva et al. (2009) [121] |
GSE6891 | GEO | Human | Adult | Primary BM, PB | M0‐M6 and nondetermined | None | Microarray | Verhaak et al. (2009) [122] |
GSE24006 | GEO | Human | Adult | Primary BM, PB, cord blood | AML and healthy | None | Microarray | Gentles et al. (2010) [123] |
GSE17855 | GEO | Human | Paediatric | Primary BM, PB | MLL‐rearrangements, t(8;21)(q22;q22), Inv(16)(p13;q22), t(15;17)(q21;q22), t(7;12)(q36;p13), CN‐AML, etc. | Patients treated with Cytarabine and anthracycline | Microarray | Balgobind et al. (2011) [124] |
GSE30377 | GEO | Human | Unknown | Xenotransplanted Primary BM cells | Unknown | None | Microarray | Eppert et al. (2011) [84] |
GSE64776 | GEO | Human | Adult | Primary cells | MLL | None | Microarray | Iwasaki et al. (2015) [90] |
GSE64773 | GEO | Mouse | Unknown | Primary cells | HoxA9 Meis1 shRNA induced AML and healthy | None | Microarray | Iwasaki et al. (2015) [90] |
GSE74666 | GEO | Human | Paediatric | Cell line MV4‐11 |
AML M5 t(4;11)(q21;q23) |
Sorafenib | Microarray | Ref. [125] |
GSE76009 | GEO | Human | Adult | Primary BM, PB, peritoneal fluid | APL, non‐APL | None | Microarray | Ng et al. (2016) [85] |
GSE81842 | GEO | Mouse | Unknown | Primary BM, PB, spleen, gonadal adipose tissue | BCR‐ABL and NUP98‐HOXA9 | None | RNA‐Seq | Ye et al. (2016) [116] |
GSE92778 | GEO | Human | Adult | Cultured Primary BM cells from patients | AML and healthy | None | Microarray | Boyd et al. (2017) [126] |
GSE107662 | GEO | Mouse | 0 – 52w |
Primary FL, BM |
NUP98‐HOXA9 retrovirus | None | RNA‐Seq | Chaudhury et al. (2018) [23] |
GSE122066 | GEO | Mouse | 3w, 52w | Primary BM | LSK, non‐AML | None | RNA‐Seq | Chaudhury et al. (2018) [23] |
GSE114111 | GEO | Human | Adult |
Cell line MOLM‐13 |
ins(11;9)(q23;p22p23) | FIS1‐shRNA | RNA‐Seq | Pei et al. (2018) [80] |
GSE114109 | GEO | Human | Adult |
Primary BM, PB |
Multiple cytogenetics | FIS1‐shRNA | RNA‐Seq | Pei et al. (2018) [80] |
GSE114105 | GEO | Human | Adult |
Primary BM, PB |
Multiple cytogenetics | PRKAA1‐shRNA | RNA‐Seq | Pei et al. (2018) [80] |
GSE116567 | GEO | Human | Adult |
Primary BM, PB |
Multiple cytogenetics | Untreated, venetoclax and azacitidine | RNA‐Seq | Jones et al. (2018) [79] |
GSE134506 | GEO | Human | Adult | Cell line HEL | AML M6 | Doxorubicin, Cytarabine, Decitabine | Microarray | Caiado et al. (2019) [71] |
TARGET | https://ocg.cancer.gov/programs/target/data‐matrix | Human | Paediatric | Primary cells | t(6;9), t(8;21), t(3;5)(q25;q34), t(6;11)(q27;q23), t(9;11)(p22;q23), t(10;11)(p11.2;q23), t(11:19)(q23:p13.1), inv(16), del5q, del7q, del9q, MLL | None | RNA‐Seq and microarray | Duployez et al. (2019) [92] |
E‐MTAB‐7729 | Array Express | Human | Paediatric | Primary cells | TAM and ML‐DS | None | Microarray | Labuhn et al. (2019) [45] |
GSE116256 | GEO | Human | Adult | Primary BM, cell lines MUTZ‐3, OCI‐AML‐3 | AML and healthy | Untreated and treated patients (multiple drugs) | scRNA‐Seq | van Galen et al. (2019) [67] |