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. 2021 Feb 23;35(9):2658–2671. doi: 10.1038/s41375-021-01158-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — The levels of C5a protein in conditioned media harvested from BMMNC from WT or Casp1-KO (upper panel) mobilized by G-CSF or AMD3100 and from WT or Nlrp3-KO BMMNCs (lower panel), in the presence or absence of IL-1β+IL-18 and in the presence of IL-1β + IL-18 + DAMPs (eATP, HMGB1, S1009A) were measured by ELISA. The data represent the mean value for two independent experiments (*p ≤ 0.05 and ^#p ≤ 0.005).