Table 3:

Key Variables and Data Sources for Objectives 1.1, 1.2. 2.1 and 2.2

Key Variable	Source	Sub-Protocol	Frequency
Reach (Individual-level analyses of the proportion and characteristics of the target population that received the intervention along the cascade of care)
% of loss to follow-up (LTF) patients screened for CMDs at community level *	Clinic records	Secondary data	Quarterly
Characteristics of (LTF) chronic care patients screened and not screened at community level	Clinic records	Secondary data	Quarterly
% of chronic care patients screened for CMDs at facility level	District Health Information System (DHIS) data	Secondary data	Quarterly
Characteristics of chronic care patients screened and not screened at facility level	Patient cohorts	Cohort	Quarterly
% of positive chronic care patients screened who screen positive for depression	Cohort data	Cohort	Once-off
Characteristics of chronic care patients who screened positive and negative*	Cohort data	Cohort	Once-off
% of chronic care patients screening positive who are diagnosed and referred	Cohort data	Cohort	Once-off
Characteristics of chronic care patients screening positive who are diagnosed and referred	Cohort data	Cohort	Once-off
% of chronic care patients referred for counselling who receive at least one counselling session	Cohort data, project records	Cohort, Secondary data	Once-off; Quarterly
Characteristics of referred patients receiving one or more counselling sessions/not receiving any sessions	Cohort data; CFIR interviews with patients receiving one or more counselling sessions and those receiving no sessions.	Cohort; Qualitative data	Once-off
% of clinic population receiving mental health treatment initiation	DHIS data	Secondary	Monthly
Effectiveness (Real-world effectiveness on patient-level outcomes)
Depressive symptoms	Patient cohorts	3-month cohort data	Once-off
Disability	Patient cohorts	3-month cohort data	Once-off
Adherence to Prescribed Medications	Patient cohorts	3-month cohort data	Once-off
Perceived Stress	Patient cohorts	3-month cohort data	Once-off
Adoption (Organizational-level outcome referring to the proportion and characteristics of settings/service providers that adopt the intervention)
Facility level rate of morning talk	Facility records	Secondary data	Monthly
Characteristics of facilities with	Facility profiles; ORIC; MICA;	Secondary data;	Annually; Once-
greater/fewer morning talks on CMDs per month.	CFIR interviews with facility managers and counsellors/health promoters.	Quantitative data; Qualitative data	off.
Facility level rate of screening of chronic care patients for CMDs	DHIS data	Secondary data	Monthly
Characteristics of facilities	Facility profiles; ORIC; MICA;	Secondary data;	Annually; Once
achieving Department of Health screening targets (35% of headcount/less than 35% of headcount	CFIR interviews with facility managers and enrolled nurses	Quantitative data; Qualitative data	off
Facility level rate of diagnosis and referral of screen positive chronic care patients for depression	Cohort	Cohort data	Once-off
Characteristics of facilities with	Facility profiles; ORIC; MICA;	Secondary data;	Annually; Once
higher/lower rate of diagnosis and referral of screen positive chronic care patients for depression	CFIR interviews with facility managers and PHC nurses	Quantitative data; Qualitative data	off
Facility level rate of referred patients’ uptake of one or more counselling sessions	MhINT Project records	Secondary data	Quarterly
Characteristics of facilities with	Facility profiles; ORIC; MICA;	Secondary data;	Annually; Once
higher/lower referred patient uptake of one or more counselling sessions	CFIR interviews with facility managers, counsellors	Quantitative data; Qualitative data	off
Facility rate of mental health treatment initiation over time	DHIS data	Secondary	Monthly
% of providers who diagnosed one or more CMD patients	MhINT project records	Secondary data	Monthly
Characteristics of providers who refer/don’t refer	CFIR interviews with nurses who refer/don’t refer	Qualitative data	Once off
Implementation (Extent to which the intervention was implemented with consistency and fidelity along the cascade of care, adaptations made during the study, and cost)
Consistency of morning talks over time per facility	Facility records; CFIR interviews with facility managers and counsellors/health promoters;	Secondary data; Qualitative data	Quarterly; Once-off
Quality and consistency of screening over time per facility	Facility records; CFIR interviews with facility managers and enrolled nurses;	Secondary data; Qualitative data	Quarterly; Once-off
Quality & consistency of diagnosis & referrals per facility	Cohort; MhINT project records over time; CFIR interviews with facility managers and PHC nurses.	Cohort; Secondary data; Qualitative data	Quarterly;;;Once- off
Fidelity of counselling intervention	Fidelity checklists; CFIR interviews with clinic counsellors.	MhINT project data; Qualitative data	Once-off
Cost of intervention*	Costing analysis	Costing	Quarterly
Adaptations to intervention	Project CQI records; CFIR interviews with facility managers	Secondary data; Qualitative data	Quarterly; Once-off
Maintenance (Organizational-level institutionalization of the programme over time, as well as the individual-level sustainability of health outcomes)
Stability of effects of the intervention on patient level outcomes of effectiveness over time	Patient Cohort	3 and 9-month cohort data	Once-off
Characteristics of patients who	Patient Cohort; CFIR interviews	3 and 9-month	Once-off
had stability of effects over time	with patients who maintained	cohort data;
and those that didn’t	stability of effects over time and those that relapsed.	Qualitative data
Institutionalization of intervention	Audit of routine use of MhINT tools, processes and training materials at district level; CFIR interviews with district managers.	Secondary data; Qualitative data.	Once-off

^*Data only collected in step 3 when revised ‘scale-up unit’ is assessed