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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Nat Neurosci. 2021 Jul 8;24(9):1235–1242. doi: 10.1038/s41593-021-00879-5

Extended Data Fig. 2. Gene density and expression in LADs identified in mouse brain NPCs in vivo.

Extended Data Fig. 2

a, Circos plot showing LaminB enrichment and LADs (horizontal bars) across the mouse chromosomes (1–19) in dorsal and ventral NPCs. b, LAD and inter-LADs gene density in brain NPCs (GO-CaRT) and indicated cultured cell lines (DamID). ASCs, astrocytes., ESCs, embryonic stem cells. c, Box plot depicting average gene expression in LADs (dorsal, n=3683; ventral, n= 3520) and inter-LADs (dorsal, n=18849; ventral, n=19014) as determined by RNA-seq in dorsal and ventral NPCs, n= number of genes. p= Two-tailed students t-test. Boxes show the range from lower (25th percentile) to upper quartiles (75th percentile), with the median line (50th percentile); whiskers extend 1.5 times the inter-quartile range from bounds of box.